tests related to orientation and immediate recall) in patients with MCI. Finally, the MMSE-2 was divided into three factors (tests related to working memory and frontal lobe functioning vs. tests related to episodic memory) in patients with AD. Moreover, the MMSE-2 was divided into two factors (tests related overall cognitive functioning other than memory vs. tests that are not sensitive to decline in cognitive functions) in normal cognitive aging. The MMSE-2 was divided into two factors (tests that are sensitive to decline in cognitive functions vs.
The MMSE-2 performed well in discriminating participants across Clinical Dementia Rating (CDR) stages and CDR-Sum of Boxes (CDR-SOB), and it showed excellent internal consistency, high test-retest reliability, high interrater reliability, and good concurrent validity with the MMSE and other detailed neuropsychological assessments.
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